图书基本信息

书名: Washout Rate of Tc-99m Mibi in Bone and Soft-Tissue Sarcomas
作者: Sohaib Muhammad
ISBN13: 9783659580505
类型: 平装-胶订
语种: 英语
出版日期: 2014-07-28
出版社: LAP Lambert Academic Publishing
页数(仅供参考,以实物为准): 80

商品简介

Neoadjuvant therapy is employed before the primary treatment of sarcomas. It is not uncommon that it fails due to multi-drug resistance gene causing unnecessary delays in surgery. Tc-99m MIBI, a radiopharmaceutical, is taken-up in these tumours. Being substrate of P-glycoprotein (Pgp), its washout from the malignant tissue may predict the response of sarcoma to neoadjuvant therapy. This book presents the author's experience of in-vivo quantitative estimation of the washout rates of Tc-99m MIBI from nuclear medicine scans of various bone and soft-tissue sarcomas. These rates were then assessed for their ability to predict the effectiveness of neoadjuvant therapy initiated afterwards.